Quinolines and derivatives
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Filtered Search Results
Selleck Chemical LLC Propidium Iodide
Propidium iodide (PI) is a red-fluorescent DNA stain which penetrates only damaged cellular membranes Propidium iodide (PI) is described for use in the determination of cell viability in cell suspension
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Medchemexpress LLC Propidium Iodide | 25535-16-4 | 99.7% | 50 MG
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Propidium Iodide (PI) is a nuclear staining agent that stains DNA. It is an analogue of ethidine bromide, which emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. It is commonly used in the detection of apoptosis or necrosis, and is often used in flow cytometry analysis.
- Nuclear staining agent for DNA.
- Emits red fluorescence upon embedding in double-stranded DNA.
- Cannot pass through living cell membranes, but stains nuclei of cells with damaged membranes.
- Fluorescence wavelength of 493/617 nm, and 536/635 nm after Mosaic with DNA.
- Commonly used in detection of apoptosis or necrosis.
- Often used in flow cytometry analysis.
- Can be used in cell cycle and cell viability assays.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000586673 DIHYDROETHIDIUM SOL 500UL
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Medchemexpress LLC Propidium (iodide) | 25535-16-4 | 99.7% | 25 MG
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Propidium Iodide (PI) is a nuclear staining agent that binds to DNA, emitting red fluorescence upon embedding in double-stranded DNA. This analogue of ethidine bromide is commonly used in the detection of apoptosis or necrosis, and is often utilized in flow cytometry analysis due to its inability to pass through intact cell membranes, only staining nuclei in cells with damaged membranes.
- Emits red fluorescence upon DNA binding.
- Fluorescence wavelength: 493/617 nm.
- Wavelength after DNA mosaic: 536/635 nm.
- Permeates only damaged cell membranes.
- Targeted as a fluorescent dye for DNA/RNA synthesis.
- Emission maximum (Em): 615.
- Excitation maximum (Ex): 535.
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Cayman Chemical CellBased Propidium Iodide So
CellBased Propidium Iodide So
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Medchemexpress LLC Propidium Iodide | 25535-16-4 | 99.7% | 500 MG
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Propidium Iodide | 25535-16-4 | 99.7% | 500 MG
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Selleck Chemical LLC Chelerythrine Chloride (NSC 646662) S1292-25mg
Chelerythrine Chloride (NSC 646662 Broussonpapyrine) is a potent selective antagonist of PKC with IC50 of 0 66 M
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Medchemexpress LLC Dimidium bromide | 518-67-2 | 98.6% | 100 MG
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Dimidium bromide is a biochemical reagent suitable for use as a biological material or organic compound in life science research.
- Biochemical reagent
- Biological material
- Organic compound
- Suitable for life science related research
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Medchemexpress LLC Dimidium bromide | 518-67-2 | 98.6% | 1 G
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Dimidium bromide is a biochemical reagent used in life science research as a biological material or organic compound.
- Solid appearance
- Pale purple to purple color
- Store at room temperature, sealed, away from moisture and light
- In solvent, store at -80°C for 1 year or -20°C for 6 months
- Soluble in DMSO (125 mg/mL)
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Apexbio Technology LLC Chelerythrine Chloride 3895-92-9 10mM (in 1mL DMSO)
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Chelerythrine Chloride (CAS 3895-92-9) is a benzophenanthridine alkaloid widely utilized as a selective antagonist of protein kinase C (PKC) with an IC50 of 0 66 M It acts as a high-specificity inhibitor by targeting the kinase regulatory domain serving as a competitive inhibitor with respect to phosphate receptors and a non-competitive inhibitor toward ATP Chelerythrine also inhibits Bcl-xL inducing apoptosis in mouse embryonic fibroblasts (MEFs) with an IC50 of 1 1 M It activates the JNK1 and p38 pathways via MEKK1 and MKK4 contributing to its pro-apoptotic effects In cellular assays chelerythrine reduces cell viability (MTT IC50 2 6 M) and in animal studies promotes apoptosis through reactive oxygen species generation Its applications extend to research on kinase activity apoptosis antimicrobial activity and anti-inflammatory processes
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Cayman Chemical Propidium Iodide Solution
PI binds to double-stranded DNA and RNA after cells have been permeabilized. Once bound to nucleic acids, the nuclei appear red in color as observed by fluorescence microscopy with a rhodamine filter. PI is useful for multi-color fluorescent staining analysis. The bright red staining of nuclei makes this an excellent counter stain to be used simultaneously with FITC, PE, or Cy5. For analysis by flow cytometry, PI staining can be monitored in the FL2 channel. PI can also be used to measure cell viability since this dye is excluded from viable cells.
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Medchemexpress LLC Act-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 1 MG
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Act-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 1 MG
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Medchemexpress LLC Chelerythrine chloride | 3895-92-9 | >98.0% | 5MG
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Chelerythrine chloride | 3895-92-9 | >98.0% | 5MG
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Medchemexpress LLC EthD (bromide) | 1239-45-8 | 99.3% | 1 ML
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EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
- Fluorescent tag (nucleic acid stain) for molecular biology laboratories.
- Used in techniques such as agarose gel electrophoresis.
- Allows visualization of DNA under ultraviolet (UV) light.
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Medchemexpress LLC Chelerythrine chloride | 3895-92-9 | >98.0% | 50 MG
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Chelerythrine chloride is a cell-permeable inhibitor of protein kinase C used in biochemical and cell biology research to study PKC-dependent signaling, apoptosis, and autophagy. It is supplied as a research-grade chemical with high purity.
- Cell-permeable protein kinase C inhibitor.
- Reported PKC IC50 660 nM.
- Inhibits Bcl-XL-Bak BH3 peptide binding (IC50 1.5 μM).
- Purity >98% by HPLC.
- Molecular formula C21H18ClNO4; molecular weight ~383.8 g/mol.
- Supplied as a 50 mg vial for research use.
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